Dr. Diána Balogh-Weiser 
egyetemi docens

Education, titles

2016: Ph.D. degree (PhD thesis, BME)

2015: Biomedical engineer, M.Sc. (BME – Semmelweis University)

2011: Chemical engineer, M.Sc. (BME)

Professional experiences

2018-: assistant Professor at BME, Department of Organic Chemistry and Technology and Department of Physical Chemistry and Materials Science: Coordination of research projects related to field of biotechnology, pharmaceutical science and materials science, education including lectures and laboratory practices

2015-2018: project manager at Fermentia LLC., coordination of research project related to industrial biotechnology

Research interests

Biotechnology: enzyme immobilization methods, comprehensive analysis of enzymatic reactions and structures and ligand binding, investigation of homogenous and heterogenous biocatalysis in batch and continuous-flow reactors (espically different biotransformation integrated in Lab-on-a-Chip systems), biomimetic systems (modelling of enzymatic functions)

Pharmaceutical sciences: enzyme and protein-based therapies (enzyme replacement therapies, enzyme based solid drug formulations), investigation of enzyme inhibitions and ligand binding by classic and novel Lab-on-a-Chip based methods

Materials sciences: catalyst carrier design including micro- and nanoparticles, porous materials nanofibers, nanotubes and polymer beads, advanced surface modification methods for specific catalyst immobilization or isolation techniques

Teaching activites

Chemistry of Biomolecules (lecture)

Physical chemistry laboratory practice (calorimetry, liquid-vapor phase systems)

Organic chemistry laboratory practice (preparative chemistry)

Non-conventional materials laboratory practice (gels)

Supervisor activities

Principal investigator in research project

2021-2025: Development of Lab-on-a-chip platforms for investigation of protein-ligand interaction (NRDI, FK-137582)

2020-2022: Self-assembling Multi Layer Enzyme Network for Flow Biocatalysis (CELSA-20-243)

2019-2022: Nanostructured catalyst systems for sustainable biotransformations (NRDI, PD-131467)

2019-2022: Development of nanocarrier systems to optimize automated and scalable catalytic syntheses (sub project, NRDI, TKP-NKA-BME)

Supervising 4 PhD student (3 ongoing, 1 absolved) and more than 40 studenst at BSc and MSc level

Awards

János Bolyai Research Grant (by Hungarian Academy of Science: 2021-2024)

New National Excellence Award for Young researcher Bolyai+ (by NRDI, 2021-2022)

Women in Science Excellence Award (by Nature Award-winning Association of Hungarian Women in Science, 2020)

New National Excellence Award for Postdoctoral researcher (by NRDI, 2016-2017)

Scientific publication

3 book chapters, 41 Scientific articles

Total IF: 187.210 — Number of Independent citations: 389
h-index: 16

Selected publication

F. Nagy, E. Sánta-Bell, M. Jipa, G. Hornyánszky, A. Szilágyi, K. László, G. Katona, C. Paizs, L. Poppe*, D. Balogh-Weiser*, Cross-Linked Enzyme-Adhered Nanoparticles (CLEANs) for Continuous-Flow Bioproduction, ChemSusChem, 2022, 15, e202102284.

G. Koplányi, E. Sánta-Bell, Z. Molnár, G.D. Tóth, M. Józó, A. Szilágyi, F. Ender, B. Pukánszky, B.G. Vértessy, L. Poppe, D. Balogh-Wesier*, Entrapment of Phenylalanine Ammonia-Lyase in Nanofibrous Polylactic Acid Matrices by Emulsion Electrospinning, Catalysts, 2021, 11(10), 1149.

D. Balogh-Weiser*, B. Decsi, R. Krammer, G. Dargó, F.Ender, J. Mizsei, R. Berkecz, B. Gyarmati, A. Szilágyi, R. Tőtős, C. Paizs, L. Poppe, G.T. Balogh, Magnetic Nanoparticles with Dual Surface Functions—Efficient Carriers for Metalloporphyrin-Catalyzed Drug Metabolite Synthesis in Batch and Continuous-Flow Reactors, Nanomaterials, 2020, 10(12), 2329.

D. Weiser, F. Nagy, G. Bánóczi, M. Oláh, A. Farkas, A. Szilágyi, K. László, A. Gellért, G. Marosi, S. Kemény, L. Poppe*, Immobilization engineering – How to design advanced sol-gel systems for biocatalysis? Green Chemistry, 2017, 19(16) 3927-3937.